Cellulose derivatives are most widely used in the development of formulations. Different cellulose derivatives serves different functions such as disintegrant, binding agent, gelling agent, film forming polymer. It is necessary to know the micromeritical properties such as particle size and size distribution, shape and surface area which ultimately affect formulations stability, uniformity, dissolution and drug release. Hence micromeritics is helpful in evaluation of powders and granules for IPQC and QC parameters. Flow properties such as compressibility index, angle of repose affects greatly the flow properties of powders. In our present research work we studied the micromeritical and flow properties of different cellulose derivatives and from compressibility index and hausner ration we found that ethyl cellulose , methyl cellulose and carboxymethyl cellulose shows fair, passable flow properties whereas Carbopol 940 shows very poor flow properties. From porosity values it was found that ethyl cellulose, carboxyl methyl cellulose and methyl cellulose shows close packing arrangement.
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